Infection: Inoculation of pathogen into normally sterile tissue
Systemic inflammatory response is triggered by ischaemc, inflammation, trauma, infection to protect the host from the damaging effect of insult. However, the response can be overexaggerated when the damage and insult is too great.
Systemic inflammatory response syndrome (SIRS) criteria---> 2 or more of the following:
- Temp: <36 or >38
- HR: > 90 bpm
- RR: > 20/ min
- WCC: >12 X 10^9/L or <4X10^9/L
- MAP: <65 mmHg (Systolic BP < 90 mmHg/ Diastolic BP < 60mmHg)
Severe sepsis : SIRS with organ dysfunction (SOFA criteria)
Septic shock : Sepsis-induced hypotension despite fluid resuscitation
Sepsis Organ Failure Assessment (SOFA) criteria
Goal in treating sepsis :
1. MAP > 65 mmHg (To maintain BP > 90/60 mmHg)
2. ScvO2 > 70%
3. CVP: 8-12mmHg
4. Urine output > 0.5ml/kg/h
Recap MAP calculation:
MAP : (systolic - diastolic)1/3 + diastolic
A114954
Edited by: Wong Yee Ming
3 comments:
I thought for SIRS, the criteria are:
Temp: <36 or >38
HR: > 90 bpm
RR: > 20/ min
WCC: >12 X 10^9/L or <4X10^9/L
MAP: <65 mmHg
Note: There is a lower border for normal temperature and WCC. :P
yee ming is correct.
added with:
PaCO2 < 32mmHg (alternative for RR component)
added: severe sepsis should be = Sepsis + Oragan dysfunction, hypoperdusion or hypotension.
organ hypoperfusion may inculded lactic acidosis, oliguria, acute alteration in mental status.. and ect..
Septic shock / SIRS shock = Sepsis induced arterial hypotension
by ACCP/SCCM consensus
Most prostate cancers are adenocarcinomas, cancers that arise in glandular cells of the prostate’s epithelial tissue. Prostate cancers usually progress slowly and produce no symptoms in the initial stages. Eventually, the tumor may enlarge like mine too, the prostate gland, pressing on the urethra and causing painful or frequent urination and blood in the urine. So I was so uncomfortable with this prostate cancer diseases then I decided to do online search on how to cure cancer because I well have read a lot about herbal medicine, I came across a lot of testimony how Dr Itua cure HIV/herpes then Cancer was listed below the comment.with courage I contacted Dr Itua and he sent me his herbal medicine through Courier service then I was asked to pick it up at my post office which i quickly did. I contacted Dr Itua that I have received my herbal medicine so he instructed me on how to drink it for three weeks and that is how Dr Itua Herbal Medicine cures my prostate Cancer, The treatment takes three weeks and I was cured completely. Dr Itua is a god sent and I thank him every day of my life. Contact him now On: Email:drituaherbalcenter@gmail.com/ Whatsapp:+2348149277967.
He listed that he can as well cure the following diseases below.... Cerebral Amides. Lung Cancer,Brain cancer,Esophageal cancer,Gallbladder cancer,Gestational trophoblastic disease,Head and neck cancer,Hodgkin lymphoma Intestinal cancer,Kidney cancer,Leukemia,Liver cancer,Melanoma,Mesothelioma,Multiple myeloma,Neuroendocrine tumors,Hodgkin lymphoma,Oral cancer,Ovarian cancer,Sinus cancer,Soft tissue sarcoma,Spinal cancer,Stomach cancer,Meniere's disease , Testicular cancer,Throat cancer,Thyroid Cancer,Uterine cancer,Vaginal cancer,Vulvar cancer. Alzheimer's disease,Autism,measles, tetanus, whooping cough, tuberculosis, polio and diphtheria Adrenocortical carcinoma. Alma, Uterine Cancer, Breast Cancer, Allergic diseases. Kidney cancer, Love Spell, Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Generalized dermatitis,Alzheimer's disease,Brain Tumor,Lupus,Endometrial Cancer, cerebrovascular diseases
Dementia.Colo rectal cancer, Lottery Spell, Bladder Cancer, Skin Cancer,Ovarian Cancer,Pancreatic Cancer, HIV /Aids,Brain Tumor, Herpes, Non-Hodgkin lymphoma, Inflammatory bowel disease, Copd, Diabetes, Hepatitis
Post a Comment